There are hormonally inactive APUDomas that cause endocrine disorders. For Essay, a hormonally inactive pituitary adenoma can destroy pituitary tissue and lead to hypopituitarism.
APUD classification. The term APUDoma (APUDoma) was first used by I. Szijj in 1969 to describe ACTH-secreting medullary thyroid cancer. There are two types of Essay.
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Tumor cells localize in their usual place and secrete excessive amounts of mediators or hormones characteristic of normal cells with the same localization. Examples: a. Insulinoma - originates from the beta cells of Write My Essay, is localized in the pancreas, secretes excess amounts of insulin.
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G-cell gastrinoma - originates from the gastric mucosa or duodenum, is localized there, secretes excess amounts of essay . Tumor cells localize in their usual place, but secrete mediators or hormones that are not characteristic of normal cells with the same localization. Examples: Oat cell lung cancer - often secretes ACTH and causes Cushing's syndrome. Gastrinoma from islet cells - originates from delta cells, is localized in the pancreas, but secretes gastrin, which is not normally characteristic of delta cells.